Electrical stimulation of PAG or NRM inhibits spinal thalamic cells, (i.e. spinal neurons that challenge monosynaptically to the thalamus) in laminae I, II and V so the noxious details from your nociceptors are modulated with the spinal twine level. PAG has neuronal connections to NRM. The motion of the PAG most likely occurs by activation with the… Read More

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